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Rabbit polyclonal DFNA5 antibody (A7432)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal DFNA5 antibody.
Check alternative names for the antibodyExpand
2310037D07Rik antibody|Non-syndromic hearing impairment protein 5 antibody|Nonsyndromic hearing impairment protein antibody|Anti-DFNA5 antibody – N-terminal (ab175614)
SCBT cat No: sc-79231|sc-79232|sc-393162|sc-366609|sc-79233|
Rabbit polyclonal DFNA5 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human DFNA5
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 55kDa/Observed: Refer to figures
DFNA5 antibody was tube-contained.
DFNA5 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53 . The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity . The physiological relevance of these observations is unknown (Probable).
|Protein tissue specificity|| |
Expressed in cochlea. Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta.
|Protein sequence and domain|| |
Intramolecular interactions between N- and C-terminal domains may be important for autoinhibition in the absence of activation signal. The intrinsic pyroptosis-inducing activity is carried by the N-terminal domain.Belongs to the gasdermin family.
|Protein cellular localization|| |
Cytoplasm, cytosol . Cell membrane .
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.
AntibodyPlus can customize DFNA5 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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