Rabbit polyclonal DHFR antibody (A1607)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DHFR antibody (A1607)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

DYR antibody, DHFRP1 antibody
DHFR antibody|DHFRP1 antibody|Dihydrofolate reductase antibody|DYR antibody|DYR_HUMAN antibody|EC 1.5.1.3 antibody|Anti-Dihydrofolate reductase (DHFR) antibody [EPR5285] (ab124814)

SCBT cat No: sc-136246|sc-74593|sc-377091|sc-14780|

Name

Rabbit polyclonal DHFR antibody

Catalogue No.

A1607

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DHFR

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 21kDa/Observed: Refer to Figures

Formulation

DHFR antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DHFR antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DYR antibody, DHFRP1 antibody

Database links

Human UniProt/Swiss-Prot:P00374

Protein names

DYR, DHFRP1

Protein function

Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1.

Protein tissue specificity

Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain.

Protein sequence and domain

Belongs to the dihydrofolate reductase family.; Contains 1 DHFR (dihydrofolate reductase) domain.

Background

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008]

Note

AntibodyPlus can customize DHFR antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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