Rabbit polyclonal DICER1 antibody (A6021)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal DICER1 antibody (A6021)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:1000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal DICER1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

DCR1 antibody, MNG1 antibody, Dicer antibody, HERNA antibody, RMSE2 antibody
DCR antibody|DCR1 antibody|Dicer 1 ribonuclease type III antibody|Dicer antibody|DICER_HUMAN antibody|DICER1 antibody|Double-strand-specific ribonuclease antibody|Endoribonuclease Dicer antibody|Helicase MOI antibody|Helicase with RNase motif antibody|HERNA antibody|KIAA0928 antibody|MNG1 antibody|RMSE2 antibody|Anti-Dicer antibody [13D6] – ChIP Grade (ab14601)

SCBT cat No: sc-136981|sc-25117|sc-136980|sc-393328|sc-136979|sc-30226|

Name

Rabbit polyclonal DICER1 antibody

Catalogue No.

A6021

Reactivity

Human

Immunogen

Recombinant protein of human DICER1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:1000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 218kDa/Observed: Refer to Figures

Formulation

DICER1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DICER1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DCR1 antibody, MNG1 antibody, Dicer antibody, HERNA antibody, RMSE2 antibody

Database links

Human UniProt/Swiss-Prot:Q9UPY3

Protein names

DCR1, MNG1, Dicer, HERNA, RMSE2

Protein function

Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3′ overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

Protein sequence and domain

Belongs to the helicase family. Dicer subfamily.; Contains 1 Dicer dsRNA-binding fold domain.; Contains 1 DRBM (double-stranded RNA-binding) domain.; Contains 1 helicase ATP-binding domain.; Contains 1 helicase C-terminal domain.; Contains 1 PAZ domain.; Contains 2 RNase III domains.

Protein cellular localization

Cytoplasm .

Background

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

Note

AntibodyPlus can customize DICER1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!