Rabbit polyclonal DLGAP5 antibody (A2197)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DLGAP5 antibody (A2197)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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DLGAP5 antibody, DLG7 antibody, HURP antibody, KIAA0008 antibody
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SCBT cat No:

Name

Rabbit polyclonal DLGAP5 antibody

Catalogue No.

A2197

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human DLGAP5

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 95kDa/Observed: Refer to Figures

Formulation

DLGAP5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DLGAP5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DLGAP5 antibody, DLG7 antibody, HURP antibody, KIAA0008 antibody

Database links

Human UniProt/Swiss-Prot:Q15398

Protein names

DLGAP5, DLG7, HURP, KIAA0008

Protein function

Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.

Protein tissue specificity

Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.

Protein sequence and domain

Belongs to the SAPAP family.

Protein post-translational modifications

Ubiquitinated, leading to its degradation.; Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.

Protein cellular localization

Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note: Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.

Background

DLG7 is a potential cell cycle regulator that may play a role in carcinogenesis of cancer cells and mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. The protein is also a key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.de Reynies,A., J. Clin. Oncol. 27 (7), 1108-1115 (2009)Gudmundsson,K.O., Stem Cells 25 (6), 1498-1506 (2007)Laprise,P., J. Biol. Chem. 279 (11), 10157-10166 (2004)

Research area

All research areas>Cell Cycle Proteins>HURP
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize DLGAP5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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