Rabbit polyclonal DMAP1 antibody (A2324)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DMAP1 antibody (A2324)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:4000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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DKFZp686L09142 antibody|DMAP 1 antibody|DNA methyltransferase 1 associated protein 1 antibody|DNMAP 1 antibody|DNMAP1 antibody|DNMT1 associated protein 1 antibody|DNMTAP 1 antibody|DNMTAP1 antibody|EAF 2 antibody|EAF2 antibody|FLJ11543 antibody|KIAA1425 antibody|MAT 1 mediated transcriptional repressor antibody|MGC55593 antibody|SWC 4 antibody|SWC4 antibody|zgc:55593 antibody|Anti-DMAP1 antibody – ChIP Grade (ab2848)

SCBT cat No: sc-373949|sc-47583|

Name

Rabbit polyclonal DMAP1 antibody

Catalogue No.

A2324

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DMAP1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:1000 – 1:4000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 53kDa/Observed: Refer to figures

Formulation

DMAP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DMAP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q9NPF5

Protein function

Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome – DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

Protein sequence and domain

Contains 1 SANT domain.

Protein cellular localization

Nucleus. Cytoplasm. Note: Targeted to replication foci throughout S phase by DNMT1.

Note

AntibodyPlus can customize DMAP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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