Rabbit polyclonal DPYS antibody (A6368)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DPYS antibody (A6368)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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DHP antibody, DHPase antibody
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SCBT cat No:

Name

Rabbit polyclonal DPYS antibody

Catalogue No.

A6368

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DPYS

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 56kDa/Observed: Refer to Figures

Formulation

DPYS antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DPYS antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DHP antibody, DHPase antibody

Database links

Human UniProt/Swiss-Prot:Q14117

Protein names

DHP, DHPase

Protein function

Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.

Protein tissue specificity

Liver and kidney.

Protein sequence and domain

Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Protein post-translational modifications

Carbamylation allows a single lysine to coordinate two zinc ions.

Background

Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.

Note

AntibodyPlus can customize DPYS antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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