Rabbit polyclonal DSG3 antibody (A8412)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DSG3 antibody (A8412)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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PVA antibody, CDHF6 antibody
130 kD pemphigus vulgaris antigen antibody|130 kDa pemphigus vulgaris antigen antibody|Balding antibody|Cadherin family member 6 antibody|CDHF 6 antibody|CDHF6 antibody|Desmoglein 3 antibody|Desmoglein 3 precursor antibody|Desmoglein-3 antibody|Desmoglein3 antibody|DKFZp686P23184 antibody|DSG 3 antibody|DSG3 antibody|DSG3_HUMAN antibody|Pemphigus vulgaris antigen antibody|PVA antibody|Anti-Desmoglein 3 antibody [6G2C11] (ab201968)

SCBT cat No: sc-14863|

Name

Rabbit polyclonal DSG3 antibody

Catalogue No.

A8412

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DSG3

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 108kDa/Observed: Refer to figures

Formulation

DSG3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DSG3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PVA antibody, CDHF6 antibody

Database links

Human UniProt/Swiss-Prot:P32926

Protein names

PVA, CDHF6

Protein function

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Protein tissue specificity

Epidermis, tongue, tonsil, esophagus and carcinomas.

Protein sequence and domain

Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.Contains 4 cadherin domains.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome .

Background

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Research area

All research areas>Cell Adhesion Proteins>dsg
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize DSG3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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