Rabbit polyclonal DTX2 antibody (A7398)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DTX2 antibody (A7398)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal DTX2 antibody.

Alternative names:

Check alternative names for the antibody

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RNF58 antibody
Deltex 2 antibody|deltex homolog 2 (Drosophila) antibody|deltex, Drosophila, homolog of, 2 antibody|Deltex2 antibody|DTX2 antibody|DTX2_HUMAN antibody|hDTX2 antibody|Highly similar to hPMSR6 [H.sapiens] antibody|KIAA1528 antibody|Probable E3 ubiquitin-protein ligase DTX2 antibody|Protein deltex 2 antibody|Protein deltex-2 antibody|RING finger protein 58 antibody|RNF58 antibody|Zinc ion binding protein antibody|Anti-DTX2 antibody [EPR10916] (ab170907)

SCBT cat No: sc-101938|

Name

Rabbit polyclonal DTX2 antibody

Catalogue No.

A7398

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DTX2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 67kDa/Observed: Refer to figures

Formulation

DTX2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DTX2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RNF58 antibody

Database links

Human UniProt/Swiss-Prot:Q86UW9

Protein names

RNF58

Protein function

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Protein sequence and domain

The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases.Belongs to the Deltex family.; Contains 1 RING-type zinc finger.; Contains 2 WWE domains.

Protein cellular localization

Cytoplasm . Nucleus . Note: Predominantly cytoplasmic. Partially nuclear.

Background

DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003

Note

AntibodyPlus can customize DTX2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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