Rabbit polyclonal EDA antibody (A2905)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal EDA antibody (A2905)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EDA antibody.

Alternative names:

Check alternative names for the antibody

Expand

ED1 antibody,HED antibody,EDA1 antibody,EDA2 antibody,ODT1 antibody,XHED antibody,XLHED antibody,ED1-A1 antibody,ED1-A2 antibody,STHAGX1 antibody
ECTD1 antibody|Ectodermal dysplasia 1, anhidrotic antibody|Ectodermal dysplasia protein antibody|Ectodermal dysplasia, anhidrotic (hypohydrotic) antibody|Ectodysplasin A antibody|Ectodysplasin A, membrane form antibody|Ectodysplasin A, secreted form antibody|ECTODYSPLASIN A1 ISOFORM antibody|ECTODYSPLASIN A2 ISOFORM antibody|ECTODYSPLASIN antibody|Ectodysplasin-A antibody|ED1 A1 antibody|ED1 A2 antibody|ED1 antibody|ED1 GENE antibody|Eda A1 antibody|Eda A2 antibody|eda antibody|EDA protein antibody|EDA protein homolog antibody|EDA_HUMAN antibody|EDA1 antibody|EDA1 GENE antibody|EDA2 antibody|HED antibody|HED1 antibody|ODT1 antibody|Oligodontia 1 antibody|secreted form antibody|STHAGX1 antibody|Ta antibody|Tabby antibody|Tabby protein antibody|X linked anhidroitic ectodermal dysplasia protein antibody|XHED antibody|XLHED antibody|Anti-EDA antibody (ab125233)

SCBT cat No: sc-517135|sc-18927|sc-18925|

Name

Rabbit polyclonal EDA antibody

Catalogue No.

A2905

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human EDA

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 49kDa/Observed: Refer to Figures

Formulation

EDA antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EDA antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ED1 antibody,HED antibody,EDA1 antibody,EDA2 antibody,ODT1 antibody,XHED antibody,XLHED antibody,ED1-A1 antibody,ED1-A2 antibody,STHAGX1 antibody

Database links

Human UniProt/Swiss-Prot:Q92838

Protein names

ED1,HED,EDA1,EDA2,ODT1,XHED,XLHED,ED1-A1,ED1-A2,STHAGX1

Protein function

Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R . May also play a role in cell adhesion (By similarity).; Isoform 1: Binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor EDA2R.; Isoform 3: Binds only to the receptor EDA2R.

Protein tissue specificity

Not abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord.

Protein sequence and domain

Belongs to the tumor necrosis factor family.; Contains 1 collagen-like domain.

Protein post-translational modifications

N-glycosylated.; Processing by furin produces a secreted form.

Protein cellular localization

Cell membrane ; Single-pass type II membrane protein .; Ectodysplasin-A, secreted form: Secreted .

Background

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.

Research area

All research areas>Growth Factors and Hormones>EDA
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize EDA antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!