Rabbit polyclonal EDF1 antibody (A2283)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EDF1 antibody (A2283)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EDF1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

MBF1 antibody, EDF-1 antibody
CAP19 antibody|MBF1 antibody|MGC9058 antibody|Multiprotein bridging factor 1 antibody|Multiprotein-bridging factor 1 antibody|Anti-EDF1 antibody (ab167626)

SCBT cat No: sc-70259|sc-133536|

Name

Rabbit polyclonal EDF1 antibody

Catalogue No.

A2283

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human EDF1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 16kDa/Observed: Refer to Figures

Formulation

EDF1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EDF1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MBF1 antibody, EDF-1 antibody

Database links

Human UniProt/Swiss-Prot:O60869

Protein names

MBF1, EDF-1

Protein function

Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.

Protein tissue specificity

Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.

Protein sequence and domain

The IQ motif, which is involved in calmodulin binding, overlaps with the binding domain for nuclear receptors and transcription factors. Its phosphorylation probably allows a switch between the two activities of the protein (By similarity).Contains 1 HTH cro/C1-type DNA-binding domain.

Protein post-translational modifications

Phosphorylated (by PKA and PKC).

Protein cellular localization

Cytoplasm. Nucleus. Note: Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.

Background

This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants.

Note

AntibodyPlus can customize EDF1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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