Rabbit polyclonal EEF1A1 antibody (A0974)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EEF1A1 antibody (A0974)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100 IF 1:20 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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EEF1A1 antibody,CCS-3 antibody,CCS3 antibody,EEF-1 antibody,EEF1A antibody,EF-Tu antibody,EF1A antibody,FLJ25721 antibody,GRAF-1EF antibody,HNGC:16303 antibody,LENG7 antibody,MGC102687 antibody,MGC131894 antibody,MGC16224 antibody,PTI1 antibody,eEF1A-1 antibody
CCS3 antibody|eEF1A-1 antibody|eEF1A-2 antibody|EEF1A1 antibody|Eef1a2 antibody|EEF1AL antibody|EF 1 alpha 2 antibody|EF-1-alpha-1 antibody|EF-1-alpha-2 antibody|EF-Tu antibody|EF1A antibody|EF1A1_HUMAN antibody|EF1A2_HUMAN antibody|Elongation factor 1 A 2 antibody|Elongation factor 1 alpha antibody|Elongation factor 1 alpha 2 antibody|Elongation factor 1-alpha 1 antibody|Elongation factor 1-alpha 2 antibody|Elongation factor Tu antibody|Eukaryotic elongation factor 1 A-1 antibody|Eukaryotic elongation factor 1 A-2 antibody|Eukaryotic translation elongation factor 1 alpha 2 antibody|GRAF 1EF antibody|HS1 antibody|Leukocyte receptor cluster member 7 antibody|PTI1 antibody|Statin-S1 antibody|Anti-eEF1A1+eEF1A2+eEF1AL3 antibody (ab37969)

SCBT cat No: sc-68481|

Name

Rabbit polyclonal EEF1A1 antibody

Catalogue No.

A0974

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human EEF1A1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100
IF 1:20 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 50kDa/Observed: Refer to Figures

Formulation

EEF1A1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EEF1A1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EEF1A1 antibody,CCS-3 antibody,CCS3 antibody,EEF-1 antibody,EEF1A antibody,EF-Tu antibody,EF1A antibody,FLJ25721 antibody,GRAF-1EF antibody,HNGC:16303 antibody,LENG7 antibody,MGC102687 antibody,MGC131894 antibody,MGC16224 antibody,PTI1 antibody,eEF1A-1 antibody

Database links

Human UniProt/Swiss-Prot:P68104

Protein names

EEF1A1,CCS-3,CCS3,EEF-1,EEF1A,EF-Tu,EF1A,FLJ25721,GRAF-1EF,HNGC:16303,LENG7,MGC102687,MGC131894,MGC16224,PTI1,eEF1A-1

Protein function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.

Protein tissue specificity

Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle.

Protein sequence and domain

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.; Contains 1 tr-type G (guanine nucleotide-binding) domain.

Protein post-translational modifications

ISGylated.; Phosphorylated by TXK. Phosphorylation by PASK increases translation efficiency.

Protein cellular localization

Cytoplasm. Nucleus. Nucleus, nucleolus. Note: Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens.

Background

Translation is the process where amino acid residues are assembled into polypeptides on ribosomes. This process is generally divided into three stages: initiation, elongation and termination. During elongation, mRNA and tRNA pair at the two active sites (A and P sites) on the ribosome. A number of eukaryotic elongation factors (eEFs) are involved in this process in mammalian cells (1). eEF1A, also called elongation factor Tu (EF-Tu), binds GTP and interacts with amino acyl-tRNAs to promote recruitment of amino acyl-tRNAs to the A-site of the ribosome (1). After GTP hydrolysis, GDP-eEF1A leaves the ribosome and is later converted back to the GTP-eEF1A by eEF1B (1). Studies have shown that eEF1A is phosphorylated under certain conditions, indicating that its activity is regulated at the post-translational level (2,3).

Research area

All research areas>Transcription Regulators>EF
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize EEF1A1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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