No products in the cart.
Home/Products/Product type/Primary antibody
Rabbit polyclonal EFNB2 antibody (A5669)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal EFNB2 antibody (A5669)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100
Recommended protocols: check protocols
Image descriptions:
Click or hover above images to see image description for Rabbit polyclonal EFNB2 antibody.
Alternative names:
Check alternative names for the antibody
ExpandHTKL antibody, EPLG5 antibody, Htk-L antibody, LERK5 antibody
EFN B2 antibody|MGC126226 antibody|MGC126227 antibody|MGC126228 antibody|OTTMUSP00000024973 antibody|Anti-Ephrin B2 antibody [EPR10072(B)] (ab150411)
SCBT cat No: sc-19227|sc-398735|sc-15397|sc-1010|
Name | Rabbit polyclonal EFNB2 antibody |
---|---|
Catalogue No. | A5669 |
Reactivity | Human, Mouse, Rat |
Immunogen | Recombinant protein of human EFNB2 |
Host | Rabbit |
Applications | WB, IHC, IF |
Recommended dilution | WB 1:500 – 1:2000 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Molecular weight | Predicted: 36kDa/Observed: Refer to Figures |
Formulation | EFNB2 antibody was tube-contained. |
Purification | EFNB2 antibody was purified using affinity purification. |
Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
Alternative antibody names | HTKL antibody, EPLG5 antibody, Htk-L antibody, LERK5 antibody |
Database links | Human UniProt/Swiss-Prot:P52799 |
Protein names | HTKL, EPLG5, Htk-L, LERK5 |
Protein function | Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.; (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus. |
Protein tissue specificity | Lung and kidney. |
Protein sequence and domain | Belongs to the ephrin family.; Contains 1 ephrin RBD (ephrin receptor-binding) domain. |
Protein post-translational modifications | Inducible phosphorylation of tyrosine residues in the cytoplasmic domain. |
Protein cellular localization | Membrane; Single-pass type I membrane protein. |
Background | This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. |
Research area | All research areas>Growth Factors and Hormones>Ephrin |
Note | AntibodyPlus can customize EFNB2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
Product type | Primary antibody |
Supplier | ABclonal Inc. |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below:
Reviews
There are no reviews yet.