Rabbit polyclonal EFNB2 antibody (A5669)

A5669

Recombinant protein of human EFNB2

WB, IHC, IF

Polyclonal

IgG

EFNB2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Human UniProt/Swiss-Prot:P52799

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.; (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.

Belongs to the ephrin family.; Contains 1 ephrin RBD (ephrin receptor-binding) domain.

Membrane; Single-pass type I membrane protein.

All research areas>Growth Factors and Hormones>Ephrin
(View all antibody categories related to Growth Factors and Hormones)

Primary antibody