Rabbit polyclonal EHMT1 antibody (A8513)


Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EHMT1 antibody (A8513)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EHMT1 antibody.

Alternative names:

Check alternative names for the antibody


GLP antibody, GLP1 antibody, KMT1D antibody, FP13812 antibody, EUHMTASE1 antibody, Eu-HMTase1 antibody, bA188C12.1 antibody
bA188C12.1 antibody|DKFZp667M072 antibody|EHMT 1 antibody|EHMT1 antibody|EHMT1_HUMAN antibody|Eu-HMTase1 antibody|Euchromatic histone lysine N methyltransferase 1 antibody|Euchromatic histone methyltransferase 1 antibody|Euchromatic histone-lysine N-methyltransferase 1 antibody|EUHMTASE1 antibody|FLJ12879 antibody|FP13812 antibody|G9a like protein 1 antibody|G9a like protein antibody|G9a-like protein 1 antibody|GLP 1 antibody|GLP antibody|GLP1 antibody|H3 K9 HMTase 5 antibody|H3-K9-HMTase 5 antibody|Histone H3 K9 methyltransferase 5 antibody|Histone H3-K9 methyltransferase 5 antibody|Histone lysine N methyltransferase H3 lysine 9 specific 5 antibody|Histone-lysine N-methyltransferase EHMT1 antibody|KIAA1876 antibody|Lysine N methyltransferase 1D antibody|Lysine N-methyltransferase 1D antibody|RP11 188C12.1 antibody|Anti-EHMT1/GLP antibody [B0422] – ChIP Grade (ab41969)

SCBT cat No: sc-68165|sc-130747|sc-68166|


Rabbit polyclonal EHMT1 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human EHMT1





Recommended dilution

WB 1:500 – 1:2000







Molecular weight

Predicted: 141kDa/Observed: Refer to figures


EHMT1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


EHMT1 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GLP antibody, GLP1 antibody, KMT1D antibody, FP13812 antibody, EUHMTASE1 antibody, Eu-HMTase1 antibody, bA188C12.1 antibody

Database links

Human UniProt/Swiss-Prot:Q9H9B1

Protein names

GLP, GLP1, KMT1D, FP13812, EUHMTASE1, Eu-HMTase1, bA188C12.1

Protein function

Histone methyltransferase that specifically mono- and dimethylates ‘Lys-9’ of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates ‘Lys-27’ of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of ‘Lys-373’ of p53/TP53.

Protein tissue specificity

Widely expressed.

Protein sequence and domain

The ANK repeats recognize and bind RELA subunit of NF-kappa-B, when RELA is monomethylated at ‘Lys-310’ (By similarity). They also specifically recognize and bind H3K9me1 and H3K9me2.; The SET domain mediates interaction with WIZ.; In the pre-SET domain, Cys residues bind 3 zinc ions that are arranged in a triangular cluster; some of these Cys residues contribute to the binding of two zinc ions within the cluster.Belongs to the class V-like SAM-binding methyltransferase superfamily.; Contains 8 ANK repeats.; Contains 1 pre-SET domain.; Contains 1 SET domain.

Protein cellular localization

Nucleus. Chromosome. Note: Associates with euchromatic regions.


The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.

Research area

All research areas>Transcription Regulators>EHMT
(View all antibody categories related to Transcription Regulators)


AntibodyPlus can customize EHMT1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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