Rabbit polyclonal EIF2S3 antibody (A6581)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EIF2S3 antibody (A6581)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EIF2S3 antibody.

Alternative names:

Check alternative names for the antibody

Expand

EIF2 antibody, EIF2G antibody, eIF-2gA antibody, EIF2gamma antibody
eIF-2-gamma X antibody|eIF-2gA antibody|eIF-2gX antibody|EIF2 antibody|EIF2G antibody|EIF2gamma antibody|EIF2S3 antibody|Eukaryotic translation initiation factor 2 gamma antibody|Eukaryotic translation initiation factor 2 gamma subunit antibody|Eukaryotic translation initiation factor 2 subunit 3 antibody|Eukaryotic translation initiation factor 2 subunit 3 gamma 52kDa antibody|Eukaryotic translation initiation factor 2 subunit gamma X antibody|IF2G_HUMAN antibody|Anti-EIF2G antibody (ab33207)

SCBT cat No: sc-131150|

Name

Rabbit polyclonal EIF2S3 antibody

Catalogue No.

A6581

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human EIF2S3

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 51kDa/Observed: Refer to figures

Formulation

EIF2S3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EIF2S3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EIF2 antibody, EIF2G antibody, eIF-2gA antibody, EIF2gamma antibody

Database links

Human UniProt/Swiss-Prot:P41091

Protein names

EIF2, EIF2G, eIF-2gA, EIF2gamma

Protein function

As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B (By similarity). Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage (By similarity).

Protein tissue specificity

Expressed in testis, brain, liver and muscle.

Protein sequence and domain

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.; Contains 1 tr-type G (guanine nucleotide-binding) domain.

Background

The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit.

Research area

All research areas>Signaling Intermediates>eIF
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize EIF2S3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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