Rabbit Polyclonal EIF3B antibody (A10259)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal EIF3B antibody (A10259)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal EIF3B antibody.

Alternative names:

Check alternative names for the antibody

Expand

PRT1 antibody; EIF3S9 antibody; EIF3-ETA antibody; EIF3-P110 antibody; EIF3-P116 antibody;
eIF-3-eta antibody|eIF3 eta antibody|eIF3 p110 antibody|eIF3 p116 antibody|EIF3-ETA antibody|EIF3-P110 antibody|EIF3-P116 antibody|eIF3b antibody|EIF3B_HUMAN antibody|EIF3S9 antibody|EIF3S9, formerly antibody|Eukaryotic translation initiation factor 3, subunit B antibody|Eukaryotic translation initiation factor 3 subunit 9 antibody|eukaryotic translation initiation factor 3 subunit 9 eta antibody|Eukaryotic translation initiation factor 3 subunit B antibody|eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) antibody|eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa antibody|eukaryotic translation initiation factor 3, subunit 9, formerly antibody|hPrt1 antibody|Protein synthesis defective at 36 degrees celsius 1, S. cerevisiae, homolog of antibody|PRT1 antibody|Prt1 homolog antibody|Anti-eIF3B antibody [EPR5804] (ab133601)

SCBT cat No: sc-16378|sc-137214|sc-137215|sc-28857|sc-16377|

Name

Rabbit Polyclonal EIF3B antibody

Catalogue No.

A10259

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human EIF3B

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

92kDa

Formulation

EIF3B antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PRT1 antibody; EIF3S9 antibody; EIF3-ETA antibody; EIF3-P110 antibody; EIF3-P116 antibody;

Protein names

PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116;

Protein function

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).; (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).

Protein sequence and domain

Belongs to the eIF-3 subunit B family.; Contains 1 RRM (RNA recognition motif) domain.; Contains 8 WD repeats. The RRM domain mediates interaction with EIF3J.

Protein post-translational modifications

Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

Protein cellular localization

Cytoplasm .

Note

AntibodyPlus can customize EIF3B antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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