Rabbit polyclonal EIF3E antibody (A5447)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EIF3E antibody (A5447)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EIF3E antibody.

Alternative names:

Check alternative names for the antibody

Expand

INT6 antibody, EIF3S6 antibody, EIF3-P48 antibody, eIF3-p46 antibody
eIF-3 p48 antibody|eIF3e antibody|EIF3E_HUMAN antibody|EIF3S6 antibody|eIFe antibody|Eukaryotic translation initiation factor 3 subunit 6 antibody|Eukaryotic translation initiation factor 3 subunit E antibody|eukaryotic translation initiation factor 3, subunit 6 (48kD) antibody|INT6 antibody|mammary tumor-associated protein INT6 antibody|murine mammary tumor integration site 6 (oncogene homolog) antibody|Viral integration site protein INT-6 homolog antibody|Anti-eIF3e antibody (ab36766)

SCBT cat No: sc-74506|sc-133251|sc-74505|sc-376899|sc-376821|sc-28859|sc-376110|sc-376109|

Name

Rabbit polyclonal EIF3E antibody

Catalogue No.

A5447

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human EIF3E

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 52kDa/Observed: Refer to figures

Formulation

EIF3E antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EIF3E antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

INT6 antibody, EIF3S6 antibody, EIF3-P48 antibody, eIF3-p46 antibody

Database links

Human UniProt/Swiss-Prot:P60228

Protein names

INT6, EIF3S6, EIF3-P48, eIF3-p46

Protein function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.

Protein tissue specificity

Ubiquitously expressed. Expressed at highest levels in appendix, lymph, pancreas, skeletal muscle, spleen and thymus.

Protein sequence and domain

Belongs to the eIF-3 subunit E family.; Contains 1 PCI domain.

Protein cellular localization

Cytoplasm. Nucleus, PML body.

Note

AntibodyPlus can customize EIF3E antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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