Rabbit polyclonal EIF4G1 antibody (A7552)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EIF4G1 antibody (A7552)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EIF4G1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

P220 antibody, EIF4F antibody, EIF4G antibody, EIF4GI antibody, PARK18 antibody, EIF-4G1 antibody
DKFZp686A1451 antibody|eIF 4 gamma 1 antibody|eIF 4G 1 antibody|eIF 4G1 antibody|eIF-4-gamma 1 antibody|eIF-4G 1 antibody|eIF-4G1 antibody|EIF4 gamma antibody|EIF4F antibody|EIF4G antibody|EIF4G1 antibody|EIF4GI antibody|Eukaryotic translation initiation factor 4 gamma 1 antibody|IF4G1_HUMAN antibody|p220 antibody|Anti-eIF4G1 antibody (ab2609)

SCBT cat No: sc-136142|sc-133155|sc-377288|sc-9602|sc-373892|sc-11373|sc-9601|

Name

Rabbit polyclonal EIF4G1 antibody

Catalogue No.

A7552

Reactivity

Human

Immunogen

A synthetic peptide of human EIF4G1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 175kDa/Observed: Refer to figures

Formulation

EIF4G1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EIF4G1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

P220 antibody, EIF4F antibody, EIF4G antibody, EIF4GI antibody, PARK18 antibody, EIF-4G1 antibody

Database links

Human UniProt/Swiss-Prot:Q04637

Protein names

P220, EIF4F, EIF4G, EIF4GI, PARK18, EIF-4G1

Protein function

Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5′-terminal secondary structure and recruitment of mRNA to the ribosome.

Protein sequence and domain

Belongs to the eukaryotic initiation factor 4G family.; Contains 1 MI domain.; Contains 1 MIF4G domain.; Contains 1 W2 domain.

Protein post-translational modifications

Phosphorylated at multiple sites in vivo. Phosphorylation at Ser-1185 by PRKCA induces binding to MKNK1.; Following infection by certain enteroviruses, rhinoviruses and aphthoviruses, EIF4G1 is cleaved by the viral protease 2A, or the leader protease in the case of aphthoviruses. This shuts down the capped cellular mRNA transcription.

Background

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5′-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Research area

All research areas>Signaling Intermediates>eIF
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize EIF4G1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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