Rabbit polyclonal EIF4G2 antibody (A2897)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EIF4G2 antibody (A2897)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:1000 IHC 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EIF4G2 antibody.

Alternative names:

Check alternative names for the antibody

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P97 antibody,AAG1 antibody,DAP5 antibody,NAT1 antibody
DAP-5 antibody|Death associated protein 5 antibody|Death-associated protein 5 antibody|eIF-4-gamma 2 antibody|eIF-4G 2 antibody|eIF4G 2 antibody|EIF4G2 antibody|Eukaryotic translation initiation factor 4 gamma 2 antibody|IF4G2_HUMAN antibody|Nat1 antibody|Novel APOBEC-1 target 1 antibody|p97 antibody|Translation repressor NAT1 antibody|Translation repressor NAT1 antibody|Anti-DAP5 antibody (ab97302)

SCBT cat No: sc-135999|sc-374236|sc-137131|sc-31679|sc-137011|sc-13736|sc-28224|

Name

Rabbit polyclonal EIF4G2 antibody

Catalogue No.

A2897

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human EIF4G2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:1000
IHC 1:100 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 102kDa/Observed: Refer to Figures

Formulation

EIF4G2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EIF4G2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

P97 antibody,AAG1 antibody,DAP5 antibody,NAT1 antibody

Database links

Human UniProt/Swiss-Prot:P78344

Protein names

P97,AAG1,DAP5,NAT1

Protein function

Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.

Protein tissue specificity

Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.

Protein sequence and domain

Belongs to the eukaryotic initiation factor 4G family.; Contains 1 MI domain.; Contains 1 MIF4G domain.; Contains 1 W2 domain.

Protein post-translational modifications

Phosphorylation; hyperphosphorylated during mitosis.

Background

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Research area

All research areas>Tumor Suppressor/Apoptosis>DAP
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize EIF4G2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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