Rabbit polyclonal EIF5A antibody (A2016)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EIF5A antibody (A2016)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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EIF-5A antibody, EIF5A1 antibody, eIF5AI antibody
eIF 4D antibody|eIF 5A 1 antibody|EIF 5A antibody|eIF 5A1 antibody|eIF-4D antibody|eIF-5A antibody|eIF-5A-1 antibody|eIF-5A1 antibody|eIF4D antibody|eif5a antibody|EIF5A1 antibody|eIF5AI antibody|Eukaryotic initiation factor 5A antibody|Eukaryotic initiation factor 5A isoform 1 antibody|Eukaryotic translation initiation factor 5A 1 antibody|Eukaryotic translation initiation factor 5A antibody|Eukaryotic translation initiation factor 5A-1 antibody|IF5A1_HUMAN antibody|MGC104255 antibody|MGC99547 antibody|Rev binding factor antibody|Rev-binding factor antibody|uORF A antibody|uORF antibody|Anti-eIF5A antibody [EP526Y] (ab32443)

SCBT cat No: sc-390062|sc-18939|sc-366096|sc-390202|sc-18938|

Name

Rabbit polyclonal EIF5A antibody

Catalogue No.

A2016

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human EIF5A

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 16kDa/Observed: Refer to Figures

Formulation

EIF5A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EIF5A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EIF-5A antibody, EIF5A1 antibody, eIF5AI antibody

Database links

Human UniProt/Swiss-Prot:P63241

Protein names

EIF-5A, EIF5A1, eIF5AI

Protein function

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Protein tissue specificity

Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level).

Protein sequence and domain

Belongs to the eIF-5A family.

Protein post-translational modifications

Acetylated. Deacetylated by SIRT2.; eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).

Protein cellular localization

Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note: Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.

Background

mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Research area

All research areas>Signaling Intermediates>eIF
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize EIF5A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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