Rabbit polyclonal ELAVL3 antibody (A6091)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IP,RIP
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ELAVL3 antibody (A6091)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IP,RIP

Recommended dilution:

WB 1:500 – 1:1000 IHC 1:50 – 1:200 IP 1:20 – 1:50 RIP1:20 – 1:50

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ELAVL3 antibody.

Alternative names:

Check alternative names for the antibody

Expand

HUC antibody, HUCL antibody, PLE21 antibody
ELAV (embryonic lethal abnormal vision Drosophila) like 3 (Hu antigen C) antibody|ELAV like protein 3 antibody|ELAV-like protein 3 antibody|ELAV3_HUMAN antibody|Elavl3 antibody|Embryonic lethal, abnormal vision, drosophila, homolog-like antibody|Hu antigen C antibody|Hu-antigen C antibody|HuC antibody|HUCL antibody|MGC20653 antibody|Paraneoplastic cerebellar degeneration associated antigen antibody|Paraneoplastic cerebellar degeneration-associated antigen antibody|Paraneoplastic limbic encephalitis antigen 21 antibody|PLE21 antibody|Anti-HuC antibody (ab129254)

SCBT cat No: sc-5981|sc-26421|

Name

Rabbit polyclonal ELAVL3 antibody

Catalogue No.

A6091

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human ELAVL3

Host

Rabbit

Applications

WB, IHC, IP, RIP

Recommended dilution

WB 1:500 – 1:1000
IHC 1:50 – 1:200
IP 1:20 – 1:50
RIP1:20 – 1:50

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 39kDa/Observed: Refer to Figures

Formulation

ELAVL3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ELAVL3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HUC antibody, HUCL antibody, PLE21 antibody

Database links

Human UniProt/Swiss-Prot:Q14576

Protein names

HUC, HUCL, PLE21

Protein function

Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance.

Protein tissue specificity

Brain specific.

Protein sequence and domain

RRM 1 and RRM 2 bind cooperatively to AU-rich sequences in target mRNAs. RRM 3 binds to poly-A mRNA sequences (By similarity).Belongs to the RRM elav family.; Contains 3 RRM (RNA recognition motif) domains.

Background

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research area

All research areas>Transcription Regulators>Hu
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize ELAVL3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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