Rabbit polyclonal ENO1 antibody (A1033)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ENO1 antibody (A1033)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:20 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ENO1 antibody,ENO1L1 antibody,MBP-1 antibody,MPB1 antibody,NNE antibody,PPH antibody
2-phospho-D-glycerate hydro-lyase antibody|Alpha-enolase antibody|Beta-enolase antibody|C-myc promoter-binding protein antibody|Crystallin Tau, included antibody|ENO1L1 antibody|Enolase 1, (alpha) antibody|Enolase 2 (gamma, neuronal) antibody|Enolase 2 antibody|Enolase 3 (beta, muscle) antibody|Enolase 3 antibody|Enolase alpha antibody|Enolase, beta antibody|Enolase, gamma antibody|Enolase, muscle specific antibody|Enolase, neuron specific antibody|Enolase, nonneuronal, included antibody|Gamma-enolase antibody|GSD13 antibody|MBP-1 antibody|MPB1 antibody|MSE antibody|Muscle-specific enolase antibody|Neural enolase antibody|Neuron-specific enolase antibody|NNE antibody|Non-neural enolase antibody|NSE antibody|Phosphpyruvate hydratase antibody|Plasminogen-binding protein antibody|Skeletal muscle enolase antibody|Anti-Non Neuronal Enolase antibody (ab49343)

SCBT cat No: sc-101514|sc-101515|sc-101513|sc-100812|sc-1498|sc-26424|sc-31007|sc-81794|sc-69968|sc-59943|sc-398138|

Name

Rabbit polyclonal ENO1 antibody

Catalogue No.

A1033

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ENO1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:20 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 47kDa/Observed: Refer to Figures

Formulation

ENO1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ENO1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ENO1 antibody,ENO1L1 antibody,MBP-1 antibody,MPB1 antibody,NNE antibody,PPH antibody

Database links

Human UniProt/Swiss-Prot:P06733

Protein names

ENO1,ENO1L1,MBP-1,MPB1,NNE,PPH

Protein function

Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.; MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.

Protein tissue specificity

The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.

Protein sequence and domain

Belongs to the enolase family.

Protein post-translational modifications

ISGylated.

Protein cellular localization

Cytoplasm . Cell membrane . Cytoplasm, myofibril, sarcomere, M line . Note: Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line.; Isoform MBP-1: Nucleus.

Background

Enolase is an important glycolytic enzyme involved in the interconversion of 2-phosphoglycerate to phosphoenolpyruvate. Mammalian enolase exists as three subunits: enolase-1 (alpha-enolase), enolase-2 (gamma-enolase) and enolase-3 (beta-enolase) that can form both homo- and heterodimers. Expression of the enolase isoforms differs in a tissue specific manner (1). Enolase-1 plays a key role in anaerobic metabolism under hypoxic conditions and may act as a cell surface plasminogen receptor during tissue invasion (2,3). Abnormal expression of enolase-1 is associated with tumor progression in some cases of breast and lung cancer (4-7). Alternatively, an enolase-1 splice variant (MBP-1) binds the c-myc promoter p2 and may function as a tumor suppressor. For this reason enolase-1 is considered as a potential therapeutic target in the treatment of some forms of cancer (8).

Research area

All research areas>Signaling Intermediates>Enolase
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize ENO1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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