Rabbit polyclonal EPB41 antibody (A2490)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal EPB41 antibody (A2490)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal EPB41 antibody.

Alternative names:

Check alternative names for the antibody

Expand

HE antibody, EL1 antibody, 4.1R antibody
4.1R antibody|41_HUMAN antibody|Band 4.1 antibody|E41P antibody|EL 1 antibody|EL1 antibody|EL1 gene antibody|Elliptocytosis 1 antibody|Elliptocytosis 1 RH linked antibody|EPB 4.1 antibody|EPB 41 antibody|EPB4.1 antibody|Epb41 antibody|Erythrocyte membrane protein band 4.1 (elliptocytosis 1 RH linked) antibody|Erythrocyte membrane protein band 4.1 antibody|Erythrocyte surface protein band 4.1 antibody|HE antibody|P4.1 antibody|Protein 4.1 antibody|Protein 4.1, red blood cell type antibody|Anti-EPB41 antibody (ab54597)

SCBT cat No: sc-398983|sc-166759|sc-514096|sc-366179|sc-25967|sc-25968|

Name

Rabbit polyclonal EPB41 antibody

Catalogue No.

A2490

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human EPB41

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 97kDa/Observed: Refer to Figures

Formulation

EPB41 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

EPB41 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HE antibody, EL1 antibody, 4.1R antibody

Database links

Human UniProt/Swiss-Prot:P11171

Protein names

HE, EL1, 4.1R

Protein function

Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.

Protein sequence and domain

Contains 1 FERM domain.

Protein post-translational modifications

Phosphorylated at multiple sites by different protein kinases and each phosphorylation event selectively modulates the protein’s functions.; Phosphorylation on Tyr-660 reduces the ability of 4.1 to promote the assembly of the spectrin/actin/4.1 ternary complex.; O-glycosylated; contains N-acetylglucosamine side chains in the C-terminal domain.

Protein cellular localization

Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Nucleus .

Background

The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Note

AntibodyPlus can customize EPB41 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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