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Rabbit Polyclonal Ephrin-A5 antibody (STJ90078)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:40000;
Recommended protocols: check protocols
Click or hover above images to see image description for Ephrin-A5 Polyclonal Antibody.
Check alternative names for the antibodyExpand
EFNA5 antibody, EPLG7 antibody, LERK7 antibody,|EPLG7 antibody|Ephrin A5 antibody|Ephrin-A5 antibody|EPLG7 antibody|GLC1M antibody|LERK-7 antibody|LERK7 antibody|RAGS antibody|Anti-Ephrin A5 antibody (ab70114)
SCBT cat No: sc-6075|sc-20722|sc-81945|
Ephrin-A5 Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Ephrin-A5 Polyclonal Antibody detects endogenous levels of Ephrin-A5 protein.
Synthesized peptide derived from Ephrin-A5 at AA range 130-210
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:40000;
|Molecular weight|| |
Ephrin-A5 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Ephrin-A5 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Ephrin-A5 antibody, AL-1 antibody, EPH-related receptor tyrosine kinase ligand 7 antibody, LERK-7 antibody
|Protein names|| |
Ephrin-A5 , AL-1 , EPH-related receptor tyrosine kinase ligand 7 , LERK-7
|Protein function|| |
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
|Protein sequence and domain|| |
Belongs to the ephrin family. / Contains 1 ephrin RBD (ephrin receptor-binding) domain.
|Protein cellular localization|| |
Cell membrane / Lipid-anchor > GPI-anchor / Membrane > caveola / Lipid-anchor > GPI-anchor
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St John’s Laboratory Ltd.
|Product type|| |
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