Rabbit polyclonal ERG antibody (A1240)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ERG antibody (A1240)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ERG antibody,erg-3 antibody,p55 antibody
v ets erythroblastosis virus E26 oncogene homolog antibody|v ets erythroblastosis virus E26 oncogene like antibody|v ets erythroblastosis virus E26 oncogene like isoform 2 antibody|v-ets erythroblastosis virus E26 oncogene antibody|v-ets erythroblastosis virus E26 oncogene homolog (avian) antibody|V-ets erythroblastosis virus E26 oncogene like (Avian), isoform CRA_e antibody|Anti-ERG antibody [EPR3864] (ab92513)

SCBT cat No: sc-376293|sc-354|sc-271048|sc-28680|

Name

Rabbit polyclonal ERG antibody

Catalogue No.

A1240

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ERG

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 55kDa/Observed: Refer to Figures

Formulation

ERG antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ERG antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ERG antibody,erg-3 antibody,p55 antibody

Database links

Human UniProt/Swiss-Prot:P11308

Protein names

ERG,erg-3,p55

Protein function

Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.

Protein sequence and domain

Belongs to the ETS family.; Contains 1 ETS DNA-binding domain.; Contains 1 PNT (pointed) domain.

Protein cellular localization

Nucleus . Cytoplasm . Note: Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Background

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing’s sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2012]

Note

AntibodyPlus can customize ERG antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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