Rabbit polyclonal ETFA antibody (A7670)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ETFA antibody (A7670)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

EMA antibody, GA2 antibody, MADD antibody
Alpha ETF antibody|Alpha-ETF antibody|Electron transfer flavoprotein alpha polypeptide antibody|Electron transfer flavoprotein alpha subunit antibody|Electron transfer flavoprotein subunit alpha mitochondrial antibody|Electron transfer flavoprotein subunit alpha, mitochondrial antibody|Electron transferring flavoprotein alpha polypeptide antibody|EMA antibody|ETFA antibody|ETFA_HUMAN antibody|GA2 antibody|Glutaric aciduria II antibody|Anti-ETFA antibody [2B11AE8] (ab110316)

SCBT cat No: sc-66219|sc-366893|sc-365982|

Name

Rabbit polyclonal ETFA antibody

Catalogue No.

A7670

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ETFA

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 35kDa/Observed: Refer to figures

Formulation

ETFA antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ETFA antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EMA antibody, GA2 antibody, MADD antibody

Database links

Human UniProt/Swiss-Prot:P13804

Protein names

EMA, GA2, MADD

Protein function

The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

Protein sequence and domain

Domain I shares an identical polypeptide fold with the beta subunit ETFB though there is no sequence similarity.Belongs to the ETF alpha-subunit/FixB family.

Protein post-translational modifications

The N-terminus is blocked.

Protein cellular localization

Mitochondrion matrix.

Background

ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize ETFA antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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