Rabbit polyclonal ETHE1 antibody (A10142)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ETHE1 antibody (A10142)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:200 – 1:1000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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Ethe1 antibody|ETHE1 protein, mitochondrial precursor antibody|ETHE1_HUMAN antibody|ethylmalonic encephalopathy 1 antibody|Ethylmalonic encephalopathy protein 1 antibody|hepatoma subtracted clone one antibody|Hepatoma subtracted clone one protein antibody|HSCO antibody|mitochondrial antibody|Protein ETHE1 antibody|Protein ETHE1 mitochondrial antibody|YF13H12 antibody|Anti-ETHE1 antibody [EPR11697] (ab174302)

SCBT cat No: sc-393869|

Name

Rabbit polyclonal ETHE1 antibody

Catalogue No.

A10142

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ETHE1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:200 – 1:1000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to figures

Formulation

ETHE1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ETHE1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:O95571

Protein function

Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus .

Protein tissue specificity

Ubiquitously expressed.

Protein sequence and domain

Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

Protein cellular localization

Cytoplasm . Nucleus . Mitochondrion matrix .

Note

AntibodyPlus can customize ETHE1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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