Rabbit polyclonal ETS1 antibody (A1596)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ETS1 antibody (A1596)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ETS-1 antibody, EWSR2 antibody
Avian erythroblastosis virus E26 (v ets) oncogene homolog 1 antibody|C ets 1 protein antibody|ETS 1 antibody|Ets protein antibody|ETS1 antibody|ETS1 protein antibody|ETS1_HUMAN antibody|EWSR 2 antibody|EWSR2 antibody|FLJ10768 antibody|P54 antibody|Protein C-ets-1 antibody|v ets avian erythroblastosis virus E2 oncogene homolog antibody|v ets avian erythroblastosis virus E26 oncogene homolog 1 antibody|v ets erythroblastosis virus E26 oncogene homolog 1 antibody|v-ets erythroblastosis virus E26 oncogene homolog 1 antibody|Anti-ETS1 antibody (ab26096)

SCBT cat No: sc-350|sc-55581|sc-111|sc-112|

Name

Rabbit polyclonal ETS1 antibody

Catalogue No.

A1596

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein of human ETS1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 50kDa/Observed: Refer to Figures

Formulation

ETS1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ETS1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ETS-1 antibody, EWSR2 antibody

Database links

Human UniProt/Swiss-Prot:P14921

Protein names

ETS-1, EWSR2

Protein function

Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.

Protein tissue specificity

Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney.

Protein sequence and domain

Belongs to the ETS family.; Contains 1 ETS DNA-binding domain.; Contains 1 PNT (pointed) domain.

Protein post-translational modifications

Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2; which inhibits transcriptional activity.; Ubiquitinated; which induces proteasomal degradation.

Protein cellular localization

Cytoplasm . Nucleus . Note: Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.

Background

This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Note

AntibodyPlus can customize ETS1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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