Rabbit polyclonal ETV6 antibody (A1637)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ETV6 antibody (A1637)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ETV6 antibody.

Alternative names:

Check alternative names for the antibody

Expand

TEL antibody, TEL/ABL antibody
ETV 6 antibody|ETV6 antibody|ETV6_HUMAN antibody|Tel antibody|TEL oncogene antibody|TEL/ABL antibody|TEL1 antibody|TEL1 oncogene antibody|Transcription factor ETV 6 antibody|Transcription factor ETV6 antibody|Anti-ETV6 / Tel antibody (ab185816)

SCBT cat No:

Name

Rabbit polyclonal ETV6 antibody

Catalogue No.

A1637

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ETV6

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 53kDa/Observed: Refer to Figures

Formulation

ETV6 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ETV6 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TEL antibody, TEL/ABL antibody

Database links

Human UniProt/Swiss-Prot:P41212

Protein names

TEL, TEL/ABL

Protein function

Transcriptional repressor; binds to the DNA sequence 5′-CCGGAAGT-3′. Plays a role in hematopoiesis and malignant transformation.

Protein tissue specificity

Ubiquitous.

Protein sequence and domain

Belongs to the ETS family.; Contains 1 ETS DNA-binding domain.; Contains 1 PNT (pointed) domain.

Protein post-translational modifications

Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression.

Protein cellular localization

Nucleus.

Background

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]

Research area

All research areas>Transcription Regulators>TEL
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize ETV6 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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