Rabbit polyclonal F2R antibody (A5641)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal F2R antibody (A5641)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal F2R antibody.

Alternative names:

Check alternative names for the antibody

Expand

TR antibody, HTR antibody, CF2R antibody, PAR1 antibody, PAR-1 antibody
CF2R antibody|Coagulation factor II (thrombin) receptor antibody|Coagulation factor II receptor antibody|F2R antibody|HTR antibody|PAR 1 antibody|PAR-1 antibody|PAR1 antibody|PAR1_HUMAN antibody|Protease activated receptor 1 antibody|Proteinase activated receptor 1 antibody|Proteinase-activated receptor 1 antibody|Thrombin receptor antibody|TR antibody|Anti-Thrombin Receptor antibody (ab32611)

SCBT cat No:

Name

Rabbit polyclonal F2R antibody

Catalogue No.

A5641

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human F2R

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 47kDa/Observed: Refer to figures

Formulation

F2R antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

F2R antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TR antibody, HTR antibody, CF2R antibody, PAR1 antibody, PAR-1 antibody

Database links

Human UniProt/Swiss-Prot:P25116

Protein names

TR, HTR, CF2R, PAR1, PAR-1

Protein function

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Protein tissue specificity

Platelets and vascular endothelial cells.

Protein sequence and domain

The cleaved signal peptide may not be degraded and may function as an intracellular angiogenesis inhibitor peptide known as parstatin.Belongs to the G-protein coupled receptor 1 family.

Protein post-translational modifications

A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.; Phosphorylated in the C-terminal tail; probably mediating desensitization prior to the uncoupling and internalization of the receptor.

Protein cellular localization

Cell membrane; Multi-pass membrane protein.

Background

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member.

Research area

All research areas>Membrane Receptors>PAR
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize F2R antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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