Rabbit polyclonal F2RL3 antibody (A8471)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal F2RL3 antibody (A8471)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal F2RL3 antibody.

Alternative names:

Check alternative names for the antibody

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PAR4 antibody
Coagulation factor II (thrombin) receptor like 3 antibody|Coagulation factor II receptor like 3 antibody|Coagulation factor II receptor-like 3 antibody|F2RL3 antibody|PAR 4 antibody|PAR-4 antibody|PAR4 antibody|PAR4_HUMAN antibody|protease activated receptor 4 antibody|protease activated receptor4 antibody|Proteinase activated receptor 4 antibody|Proteinase-activated receptor 4 antibody|Thrombin receptor like 3 antibody|Thrombin receptor-like 3 antibody|Anti-Proteinase Activated Receptor 4 antibody (ab56359)

SCBT cat No: sc-293206|sc-1666|sc-1249|

Name

Rabbit polyclonal F2RL3 antibody

Catalogue No.

A8471

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human F2RL3

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 41kDa/Observed: Refer to figures

Formulation

F2RL3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

F2RL3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PAR4 antibody

Database links

Human UniProt/Swiss-Prot:Q96RI0

Protein names

PAR4

Protein function

Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.

Protein tissue specificity

Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.

Protein sequence and domain

Belongs to the G-protein coupled receptor 1 family.

Protein post-translational modifications

A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Protein cellular localization

Cell membrane; Multi-pass membrane protein.

Background

Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

Research area

All research areas>Membrane Receptors>PAR
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize F2RL3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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