Rabbit polyclonal FABP4 antibody (A0232)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FABP4 antibody (A0232)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FABP4 antibody.

Alternative names:

Check alternative names for the antibody

Expand

FABP4 antibody, aP2 antibody, ALBP antibody, Fatty acid binding protein 4 antibody, AFABP antibody, A FABP antibody
3T3-L1 lipid-binding protein antibody|422/aP2 antibody|A-FABP antibody|adipocyte antibody|Adipocyte lipid binding protein antibody|Adipocyte lipid-binding protein antibody|Adipocyte protein AP2 antibody|Adipocyte-type fatty acid-binding protein antibody|AFABP antibody|ALBP antibody|ALBP/Ap2 antibody|aP2 antibody|Epididymis secretory protein Li 104 antibody|FABP antibody|FABP4 antibody|FABP4_HUMAN antibody|Fatty acid binding protein 4 adipocyte antibody|Fatty acid binding protein 4 antibody|Fatty acid binding protein adipocyte antibody|Fatty acid-binding protein 4 antibody|Fatty acid-binding protein antibody|HEL S 104 antibody|Lbpl antibody|Myelin P2 protein homolog antibody|P15 antibody|P2 adipocyte protein antibody|Protein 422 antibody|Anti-FABP4 antibody [EPR3579] (ab92501)

SCBT cat No: sc-271529|sc-18661|

Name

Rabbit polyclonal FABP4 antibody

Catalogue No.

A0232

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FABP4

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 15kDa/Observed: Refer to Figures

Formulation

FABP4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FABP4 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FABP4 antibody, aP2 antibody, ALBP antibody, Fatty acid binding protein 4 antibody, AFABP antibody, A FABP antibody

Database links

Human UniProt/Swiss-Prot:P15090

Protein names

FABP4, aP2, ALBP, Fatty acid binding protein 4, AFABP, A FABP

Protein function

Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).

Protein sequence and domain

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein cellular localization

Cytoplasm. Nucleus. Note: Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity).

Background

Fatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). The predominant fatty acid binding protein found in adipocytes is FABP4, also called adipocyte fatty acid binding protein or aP2. FABP4 is also expressed in macrophages (3). FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes (4). Mice deficient in both FABP4 and ApoE show protection against atherosclerosis when compared with mice deficient only in ApoE (3). Mice carrying a FABP4 genetic variant exhibit both reduced FABP4 expression and a reduced potential for developing type 2 diabetes and coronary heart disease. A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders (1).

Research area

All research areas>Transport and Trafficking>A-FABP
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize FABP4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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