Rabbit Polyclonal FADS2 antibody (A10270)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal FADS2 antibody (A10270)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal FADS2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

D6D antibody; DES6 antibody; TU13 antibody; FADSD6 antibody; LLCDL2 antibody; SLL0262 antibody;
D6D antibody|Delta(6) desaturase antibody|Delta(6) fatty acid desaturase antibody|Delta-6 desaturase antibody|DES 6 antibody|DES6 antibody|FADS 2 antibody|FADS2 antibody|FADS2_HUMAN antibody|FADSD 6 antibody|FADSD6 antibody|Fatty acid desaturase 2 antibody|linoleoyl-CoA desaturase (delta-6-desaturase) like 2 antibody|LLCDL 2 antibody|LLCDL2 antibody|SLL0262 antibody|TU 13 antibody|TU13 antibody|Anti-FADS2 antibody – N-terminal (ab170665)

SCBT cat No: sc-98480|sc-109272|

Name

Rabbit Polyclonal FADS2 antibody

Catalogue No.

A10270

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human FADS2

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

52kDa

Formulation

FADS2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

D6D antibody; DES6 antibody; TU13 antibody; FADSD6 antibody; LLCDL2 antibody; SLL0262 antibody;

Protein names

D6D; DES6; TU13; FADSD6; LLCDL2; SLL0262;

Protein function

Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum.

Protein tissue specificity

Expressed in a wide array of tissues, highest expression is found in liver followed by brain, lung, heart, and retina. A lower level is found in breast tumor when compared with normal tissues; lowest levels were found in patients with poor prognostic index.

Protein sequence and domain

Belongs to the fatty acid desaturase type 1 family.; Contains 1 cytochrome b5 heme-binding domain. The histidine box domains may contain the active site and/or be involved in metal ion binding.

Protein cellular localization

Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Background

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Note

AntibodyPlus can customize FADS2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below: