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Rabbit polyclonal FAIM3 antibody (A6320)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal FAIM3 antibody.
Check alternative names for the antibodyExpand
FCMR antibody, TOSO antibody
Faim3 antibody|FAIM3_HUMAN antibody|Fas apoptotic inhibitory molecule 3 antibody|Fc fragment of IgM receptor antibody|Fc mu receptor antibody|FCMR antibody|IgM Fc receptor antibody|Immunoglobulin mu Fc receptor antibody|Regulator of Fas induced apoptosis antibody|Regulator of Fas-induced apoptosis Toso antibody|TOSO antibody|Anti-FAIM3 antibody (ab56487)
SCBT cat No:
Rabbit polyclonal FAIM3 antibody
|Catalogue No.|| |
Recombinant protein of human FAIM3
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 43kDa/Observed: Refer to Figures
FAIM3 antibody was tube-contained.
FAIM3 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
FCMR antibody, TOSO antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
|Protein tissue specificity|| |
Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat, CEM-T4, MOLT-4, HB11;19 and Reh. No expression detected in nonhematopoietic cell lines including Hep-G2, HEK293 and HeLa. Detected at high levels in chronic lymphocytic leukemia cells.
|Protein sequence and domain|| |
The Ig-like domain is required for the anti-apoptotic ability.Contains 1 Ig-like (immunoglobulin-like) domain.
|Protein cellular localization|| |
Isoform 1: Membrane ; Single-pass membrane protein .; Isoform 3: Secreted . Note: Detected in the serum.
Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009
AntibodyPlus can customize FAIM3 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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