Rabbit polyclonal FANCA antibody (A7671)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FANCA antibody (A7671)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FANCA antibody.

Alternative names:

Check alternative names for the antibody

Expand

FA antibody, FA1 antibody, FAA antibody, FAH antibody, FA-H antibody, FACA antibody, FANCH antibody
FA 1 antibody|FA antibody|FA H antibody|FA1 antibody|FAA antibody|FACA antibody|FAH antibody|Fanca antibody|FANCA_HUMAN antibody|FANCH antibody|Fanconi anemia complementation group A antibody|Fanconi anemia complementation group H antibody|Fanconi anemia group A protein antibody|Fanconi anemia type 1 antibody|MGC75158 antibody|Protein FACA antibody|Anti-FANCA antibody (ab97578)

SCBT cat No: sc-18664|sc-28215|

Name

Rabbit polyclonal FANCA antibody

Catalogue No.

A7671

Reactivity

Human

Immunogen

Recombinant protein of human FANCA

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 163kDa/Observed: Refer to figures

Formulation

FANCA antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FANCA antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FA antibody, FA1 antibody, FAA antibody, FAH antibody, FA-H antibody, FACA antibody, FANCH antibody

Database links

Human UniProt/Swiss-Prot:O15360

Protein names

FA, FA1, FAA, FAH, FA-H, FACA, FANCH

Protein function

DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.

Protein post-translational modifications

Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H.

Protein cellular localization

Nucleus. Cytoplasm. Note: The major form is nuclear. The minor form is cytoplasmic.

Background

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

Research area

All research areas>Signaling Intermediates>FANC
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize FANCA antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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