Rabbit polyclonal FBXO2 antibody (A8579)

$69.00$259.00

Reactivity: Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FBXO2 antibody (A8579)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FBXO2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

FBG1 antibody, FBX2 antibody, Fbs1 antibody, OCP1 antibody, NFB42 antibody
F box gene 1 antibody|F box only protein 2 antibody|F box protein 2 antibody|F box protein only 2 antibody|F-box only protein 2 antibody|FBG 1 antibody|FBG1 antibody|Fbs 1 antibody|Fbs1 antibody|Fbs2 antibody|FBX 2 antibody|FBX2 antibody|FBX2_HUMAN antibody|FBXO 2 antibody|FBXO2 antibody|Neural F box protein NFB42 antibody|Neural F-box protein, 42-KD, rat, homolog of antibody|NFB 42 antibody|NFB42 antibody|OCP1 antibody|organ of Corti protein 1 antibody|Prpl4 antibody|Anti-FBXO2 antibody [EPR7328(2)] (ab133717)

SCBT cat No: sc-393873|sc-69400|sc-398111|sc-69401|

Name

Rabbit polyclonal FBXO2 antibody

Catalogue No.

A8579

Reactivity

Mouse, Rat

Immunogen

Recombinant protein of human FBXO2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 33kDa/Observed: Refer to figures

Formulation

FBXO2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FBXO2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FBG1 antibody, FBX2 antibody, Fbs1 antibody, OCP1 antibody, NFB42 antibody

Database links

Human UniProt/Swiss-Prot:Q9UK22

Protein names

FBG1, FBX2, Fbs1, OCP1, NFB42

Protein function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).

Protein sequence and domain

Contains 1 F-box domain.; Contains 1 FBA (F-box associated) domain.

Protein cellular localization

Cytoplasm . Microsome membrane ; Peripheral membrane protein ; Cytoplasmic side .

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.

Research area

All research areas>Signaling Intermediates>FBXO
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize FBXO2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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