Rabbit polyclonal FCGR3B antibody (A7894)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FCGR3B antibody (A7894)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FCGR3B antibody.

Alternative names:

Check alternative names for the antibody

Expand

CD16 antibody, FCG3 antibody, CD16b antibody, FCGR3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody
CD16 antibody|CD16b antibody|CD16b antigen antibody|Fc fragment of IgG low affinity IIIb receptor antibody|Fc gamma receptor IIIb antibody|Fc gamma RIII antibody|Fc gamma RIII beta antibody|Fc gamma RIIIb antibody|Fc-gamma RIII antibody|Fc-gamma RIII-beta antibody|Fc-gamma RIIIb antibody|FCG3 antibody|FCG3B_HUMAN antibody|FCGR3 antibody|FCGR3B antibody|FcR 10 antibody|FcR-10 antibody|FcR10 antibody|FcRIII antibody|FcRIIIb antibody|IGFR3 antibody|IgG Fc receptor III 1 antibody|IgG Fc receptor III-1 antibody|Low affinity immunoglobulin gamma Fc region receptor III B antibody|Low affinity immunoglobulin gamma Fc region receptor III-B antibody|Anti-CD16b antibody [MM0272-5L11] (ab89207)

SCBT cat No:

Name

Rabbit polyclonal FCGR3B antibody

Catalogue No.

A7894

Reactivity

Human

Immunogen

Recombinant protein of human FCGR3B

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 26kDa/Observed: Refer to figures

Formulation

FCGR3B antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FCGR3B antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CD16 antibody, FCG3 antibody, CD16b antibody, FCGR3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody

Database links

Human UniProt/Swiss-Prot:O75015

Protein names

CD16, FCG3, CD16b, FCGR3, FCR-10, FCRIII, FCRIIIb

Protein function

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Protein tissue specificity

Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils.

Protein sequence and domain

Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Protein post-translational modifications

Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3.; The soluble form is produced by a proteolytic cleavage.

Protein cellular localization

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note: Secreted after cleavage.

Background

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.

Note

AntibodyPlus can customize FCGR3B antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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