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Rabbit polyclonal FDPS antibody (A5744)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal FDPS antibody.
Check alternative names for the antibodyExpand
FPS antibody, FPPS antibody
(2E antibody|(2E,6E) farnesyl diphosphate synthase antibody|6E)-farnesyl diphosphate synthase antibody|Dimethylallyltranstransferase antibody|Farnesyl diphosphate synthase antibody|Farnesyl diphosphate synthetase antibody|Farnesyl pyrophosphate synthase antibody|Farnesyl pyrophosphate synthetase antibody|Fdps antibody|FPP synthase antibody|FPP synthetase antibody|FPPS antibody|FPPS_HUMAN antibody|FPS antibody|Geranyltranstransferase antibody|Anti-FDPS antibody (ab38854)
SCBT cat No: sc-70061|
Rabbit polyclonal FDPS antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human FDPS
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 48kDa/Observed: Refer to Figures
FDPS antibody was tube-contained.
FDPS antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
FPS antibody, FPPS antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
|Protein sequence and domain|| |
Belongs to the FPP/GGPP synthase family.
|Protein cellular localization|| |
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
AntibodyPlus can customize FDPS antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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