Rabbit polyclonal FDPS antibody (A5744)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FDPS antibody (A5744)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

FPS antibody, FPPS antibody
(2E antibody|(2E,6E) farnesyl diphosphate synthase antibody|6E)-farnesyl diphosphate synthase antibody|Dimethylallyltranstransferase antibody|Farnesyl diphosphate synthase antibody|Farnesyl diphosphate synthetase antibody|Farnesyl pyrophosphate synthase antibody|Farnesyl pyrophosphate synthetase antibody|Fdps antibody|FPP synthase antibody|FPP synthetase antibody|FPPS antibody|FPPS_HUMAN antibody|FPS antibody|Geranyltranstransferase antibody|Anti-FDPS antibody (ab38854)

SCBT cat No: sc-70061|

Name

Rabbit polyclonal FDPS antibody

Catalogue No.

A5744

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FDPS

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to Figures

Formulation

FDPS antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FDPS antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FPS antibody, FPPS antibody

Database links

Human UniProt/Swiss-Prot:P14324

Protein names

FPS, FPPS

Protein function

Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.

Protein sequence and domain

Belongs to the FPP/GGPP synthase family.

Protein cellular localization

Cytoplasm.

Background

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize FDPS antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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