Rabbit polyclonal FGFBP1 antibody (A7458)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FGFBP1 antibody (A7458)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FGFBP1 antibody.

Alternative names:

Check alternative names for the antibody

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FGFBP antibody, HBP17 antibody, FGF-BP antibody, FGF-BP1 antibody, FGFBP-1 antibody
17 kDa HBGF-binding protein antibody|17 kDa heparin binding growth factor binding protein antibody|17 kDa heparin-binding growth factor-binding protein antibody|FGF binding protein 1 antibody|FGF BP antibody|FGF BP1 antibody|FGF-binding protein 1 antibody|FGF-BP antibody|FGF-BP1 antibody|FGFBP antibody|FGFBP-1 antibody|Fgfbp1 antibody|FGFP1_HUMAN antibody|Fibroblast growth factor binding protein 1 precursor antibody|Fibroblast growth factor-binding protein 1 antibody|HBp17 antibody|Anti-FGFBP1 antibody (ab67931)

SCBT cat No: sc-73991|sc-23603|

Name

Rabbit polyclonal FGFBP1 antibody

Catalogue No.

A7458

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FGFBP1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 26kDa/Observed: Refer to figures

Formulation

FGFBP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FGFBP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FGFBP antibody, HBP17 antibody, FGF-BP antibody, FGF-BP1 antibody, FGFBP-1 antibody

Database links

Human UniProt/Swiss-Prot:Q14512

Protein names

FGFBP, HBP17, FGF-BP, FGF-BP1, FGFBP-1

Protein function

Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.

Protein tissue specificity

Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas.

Protein sequence and domain

Belongs to the fibroblast growth factor-binding protein family.

Protein cellular localization

Secreted, extracellular space . Cell membrane ; Peripheral membrane protein . Note: Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.

Background

This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.

Note

AntibodyPlus can customize FGFBP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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