Rabbit polyclonal FH antibody (A5688)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FH antibody (A5688)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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MCL antibody, LRCC antibody, HLRCC antibody, MCUL1 antibody
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SCBT cat No:

Name

Rabbit polyclonal FH antibody

Catalogue No.

A5688

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FH

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 54kDa/Observed: Refer to Figures

Formulation

FH antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FH antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MCL antibody, LRCC antibody, HLRCC antibody, MCUL1 antibody

Database links

Human UniProt/Swiss-Prot:P07954

Protein names

MCL, LRCC, HLRCC, MCUL1

Protein function

Also acts as a tumor suppressor.

Protein tissue specificity

Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.

Protein sequence and domain

Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

Protein cellular localization

Isoform Mitochondrial: Mitochondrion.; Isoform Cytoplasmic: Cytoplasm.

Background

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Research area

All research areas>Signaling Intermediates>fumarate hydratase
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize FH antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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