Rabbit polyclonal FIS1 antibody (A5821)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FIS1 antibody (A5821)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FIS1 antibody.

Alternative names:

Check alternative names for the antibody

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TTC11 antibody, CGI-135 antibody
2010003O14Rik antibody|CGI 135 antibody|CGI135 antibody|FIS 1 antibody|FIS1 antibody|Fis1 homolog antibody|FIS1, S. cerevisiae, homolog of antibody|FIS1_HUMAN antibody|Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) antibody|Fission 1 (mitochondrial outer membrane) homolog (yeast) antibody|Fission 1 (mitochondrial outer membrane) homolog antibody|Fission 1 homolog antibody|H NH0132A01.6 antibody|hFis 1 antibody|hFis1 antibody|Mitochondrial fission 1 protein antibody|Tetratricopeptide repeat domain 11 antibody|Tetratricopeptide repeat protein 11 antibody|TPR repeat protein 11 antibody|TTC 11 antibody|Anti-TTC11 antibody (ab71498)

SCBT cat No: sc-376469|sc-376446|sc-98900|sc-48865|

Name

Rabbit polyclonal FIS1 antibody

Catalogue No.

A5821

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FIS1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 16kDa/Observed: Refer to Figures

Formulation

FIS1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FIS1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TTC11 antibody, CGI-135 antibody

Database links

Human UniProt/Swiss-Prot:Q9Y3D6

Protein names

TTC11, CGI-135

Protein function

Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Protein sequence and domain

The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.Belongs to the FIS1 family.; Contains 1 TPR repeat.

Protein post-translational modifications

Ubiquitinated by MARCH5.

Protein cellular localization

Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.

Background

The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003

Note

AntibodyPlus can customize FIS1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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