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Rabbit polyclonal FKBP6 antibody (A7013)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal FKBP6 antibody.
Check alternative names for the antibodyExpand
36 kDa FK506 binding protein antibody|36 kDa FK506-binding protein antibody|36 kDa FKBP antibody|EC 126.96.36.199 antibody|FK506 binding protein 6 antibody|FK506-binding protein 6 antibody|FKBP 36 antibody|FKBP-36 antibody|FKBP-6 antibody|FKBP36 antibody|fkbp6 antibody|FKBP6_HUMAN antibody|Immunophilin FKBP36 antibody|Peptidyl prolyl cis trans isomerase antibody|Peptidyl-prolyl cis-trans isomerase FKBP6 antibody|PPIase antibody|PPIase FKBP6 antibody|Rotamase antibody|Anti-FKBP6 antibody [EPR3673] (ab108419)
SCBT cat No: sc-517136|sc-104249|
Rabbit polyclonal FKBP6 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human FKBP6
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 37kDa/Observed: Refer to figures
FKBP6 antibody was tube-contained.
FKBP6 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity).
|Protein tissue specificity|| |
Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
|Protein sequence and domain|| |
Belongs to the FKBP6 family.; Contains 1 PPIase FKBP-type domain.; Contains 3 TPR repeats.
|Protein cellular localization|| |
Cytoplasm, cytosol . Nucleus . Chromosome . Note: Does not localize to pi-bodies. Localizes to meiotic chromosome cores and regions of homologous chromosome synapsis (By similarity).
The protein encoded by this gene is a cis-trans peptidyl-prolyl isomerase that may function in immunoregulation and basic cellular processes involving protein folding and trafficking. This gene is located in a chromosomal region that is deleted in Williams-Beuren syndrome. Defects in this gene may cause male infertility. There are multiple pseudogenes for this gene located nearby on chromosome 7. Alternative splicing results in multiple transcript variants.
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|Product type|| |
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