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Rabbit polyclonal FKBP8 antibody (A7085)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal FKBP8 antibody.
Check alternative names for the antibodyExpand
FKBP38 antibody, FKBPr38 antibody
38 kDa FK506-binding protein antibody|38 kDa FKBP antibody|38kDa antibody|FK506 binding protein 8 antibody|FK506 binding protein 8, 38kDa antibody|FK506 binding protein, 38kDa antibody|FK506-binding protein 8 antibody|FKBP 38 antibody|FKBP-38 antibody|FKBP-8 antibody|Fkbp8 antibody|FKBP8_HUMAN antibody|FKBPR38 antibody|hFKBP38 antibody|Peptidyl-prolyl cis-trans isomerase FKBP8 antibody|PPIase FKBP8 antibody|Rotamase antibody|Sam11 antibody|Anti-FKBP38 antibody (ab24450)
SCBT cat No: sc-166607|sc-66894|
Rabbit polyclonal FKBP8 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human FKBP8
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 45kDa/Observed: Refer to figures
FKBP8 antibody was tube-contained.
FKBP8 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
FKBP38 antibody, FKBPr38 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
|Protein tissue specificity|| |
Widely expressed. Highest levels seen in the brain. Highly abundant in the retina.
|Protein sequence and domain|| |
Contains 1 PPIase FKBP-type domain.; Contains 3 TPR repeats.
|Protein post-translational modifications|| |
Ubiquitinated by PARK2 during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
|Protein cellular localization|| |
Mitochondrion . Mitochondrion membrane ; Single-pass membrane protein; Cytoplasmic side .; Isoform 1: Mitochondrion membrane ; Single-pass membrane protein; Cytoplasmic side .; Isoform 3: Mitochondrion membrane ; Single-pass membrane protein; Cytoplasmic side .
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.
AntibodyPlus can customize FKBP8 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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