Rabbit polyclonal FMOD antibody (A6375)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FMOD antibody (A6375)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

FM antibody, SLRR2E antibody
Collagen binding 59 kDa protein antibody|Collagen-binding 59 kDa protein antibody|Fibromodulin antibody|Fibromodulin precursor antibody|Fibromodulin proteoglycan antibody|FM antibody|FMOD antibody|FMOD_HUMAN antibody|Keratan sulfate proteoglycan fibromodulin antibody|KSPG fibromodulin antibody|SLRR2E antibody|Anti-Fibromodulin antibody (ab81443)

SCBT cat No: sc-166466|sc-166498|sc-166406|sc-33772|sc-69681|

Name

Rabbit polyclonal FMOD antibody

Catalogue No.

A6375

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FMOD

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 43kDa/Observed: Refer to Figures

Formulation

FMOD antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FMOD antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FM antibody, SLRR2E antibody

Database links

Human UniProt/Swiss-Prot:Q06828

Protein names

FM, SLRR2E

Protein function

Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).

Protein sequence and domain

Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.; Contains 11 LRR (leucine-rich) repeats.; Contains 1 LRRNT domain.

Protein post-translational modifications

Binds keratan sulfate chains.

Protein cellular localization

Secreted, extracellular space, extracellular matrix.

Background

Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Note

AntibodyPlus can customize FMOD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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