Rabbit polyclonal FRZB antibody (A6592)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal FRZB antibody (A6592)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FRZB antibody.

Alternative names:

Check alternative names for the antibody

Expand

FRE antibody, OS1 antibody, FZRB antibody, hFIZ antibody, FRITZ antibody, FRP-3 antibody, FRZB1 antibody, SFRP3 antibody, SRFP3 antibody, FRZB-1 antibody, FRZB-PEN antibody
FIZ antibody|sFRP 3 antibody|SFRP antibody|Anti-FRZB antibody (ab205284)

SCBT cat No: sc-514350|sc-7427|sc-13941|

Name

Rabbit polyclonal FRZB antibody

Catalogue No.

A6592

Reactivity

Human

Immunogen

Recombinant protein of human FRZB

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 36kDa/Observed: Refer to figures

Formulation

FRZB antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FRZB antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FRE antibody, OS1 antibody, FZRB antibody, hFIZ antibody, FRITZ antibody, FRP-3 antibody, FRZB1 antibody, SFRP3 antibody, SRFP3 antibody, FRZB-1 antibody, FRZB-PEN antibody

Database links

Human UniProt/Swiss-Prot:Q92765

Protein names

FRE, OS1, FZRB, hFIZ, FRITZ, FRP-3, FRZB1, SFRP3, SRFP3, FRZB-1, FRZB-PEN

Protein function

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

Protein tissue specificity

Expressed primarily in the cartilaginous cores of the long bone during embryonic and fetal development and in the appendicular skeleton (6-13 weeks). At 13 weeks of gestation, transcripts were present in early chondroblasts of the tarsal bones of the foot, the carpal bones of the hands and the epiphysis of long bones. Highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. Weakly expressed in lung and liver.

Protein sequence and domain

The FZ domain is involved in binding with Wnt ligands.Belongs to the secreted frizzled-related protein (sFRP) family.; Contains 1 FZ (frizzled) domain.; Contains 1 NTR domain.

Protein cellular localization

Secreted .

Background

The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.

Research area

All research areas>Membrane Receptors>FRP
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize FRZB antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!