Rabbit polyclonal FTH1 antibody (A1144)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal FTH1 antibody (A1144)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal FTH1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

FTH1 antibody,FHC antibody,FTH antibody,FTHL6 antibody,MGC104426 antibody,PIG15 antibody,PLIF antibody
Apoferritin antibody|Cell proliferation inducing gene 15 protein antibody|Cell proliferation-inducing gene 15 protein antibody|F HC antibody|Ferritin H subunit antibody|Ferritin heavy chain antibody|Ferritin heavy polypeptide 1 antibody|FHC antibody|FRIH antibody|FRIH_HUMAN antibody|FTH 1 antibody|FTH antibody|FTH1 antibody|FTH1 protein antibody|FTHL 6 antibody|FTHL6 antibody|Iron overload autosomal dominant antibody|MGC104426 antibody|N-terminally processed antibody|OK/SW-cl.84 antibody|PIG 15 antibody|PIG15 antibody|Placenta immunoregulatory factor antibody|PLIF antibody|Proliferation inducing gene 15 protein antibody|Proliferation inducing protein 15 antibody|Anti-Ferritin Heavy Chain antibody [EPR3005Y] (ab75972)

SCBT cat No: sc-80786|sc-71104|sc-71102|sc-71103|

Name

Rabbit polyclonal FTH1 antibody

Catalogue No.

A1144

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FTH1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 21kDa/Observed: Refer to Figures

Formulation

FTH1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

FTH1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FTH1 antibody,FHC antibody,FTH antibody,FTHL6 antibody,MGC104426 antibody,PIG15 antibody,PLIF antibody

Database links

Human UniProt/Swiss-Prot:P02794

Protein names

FTH1,FHC,FTH,FTHL6,MGC104426,PIG15,PLIF

Protein function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

Protein tissue specificity

Expressed in the liver.

Protein sequence and domain

Belongs to the ferritin family.; Contains 1 ferritin-like diiron domain.

Background

Ferritin (FTH) is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and bioavailable form (1). The assembled ferritin molecule, often referred to as a nanocage, can store up to 4,500 atoms of iron (2,3). It forms a holoenzyme of ~450 kDa, consisting of 24 subunits made up of two types of polypeptide chains: ferritin heavy chain and ferritin light chain, each having unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe(II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe(III) (4). In addition to iron buffering, heavy chain ferritin also enhances thymidine biosynthesis (5). Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia. The level of serum ferritin is markedly elevated in inflammation, malignancy, and iron overload disorders (6). Research studies have found that defects in ferritin proteins are also associated with several neurodegenerative diseases (7).

Research area

All research areas>Signaling Intermediates>Ferritin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize FTH1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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