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Rabbit Polyclonal Gab 1 antibody (STJ93176)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for Gab 1 Polyclonal Antibody.
Check alternative names for the antibodyExpand
GAB1 antibody,|Gab 1 antibody|GAB1 antibody|GAB1_HUMAN antibody|GRB 2 associated binder 1 antibody|GRB 2 associated binding protein 1 antibody|GRB2 associated binding protein 1 isoform a antibody|GRB2 associated binding protein 1 isoform b antibody|GRB2-associated binder 1 antibody|GRB2-associated-binding protein 1 antibody|Growth factor receptor bound protein 2-associated protein 1 antibody|Anti-GAB1 antibody (ab59362)
SCBT cat No: sc-6292|sc-271848|sc-9049|sc-133191|sc-25498|
Gab 1 Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Gab 1 Polyclonal Antibody detects endogenous levels of Gab 1 protein.
Synthesized peptide derived from Gab 1 at AA range 600-680
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;
|Molecular weight|| |
Gab 1 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gab 1 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
GRB2-associated-binding protein 1 antibody, GRB2-associated binder 1 antibody, Growth factor receptor bound protein 2-associated protein 1 antibody
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q13480">Q13480</a>;Mouse UniPort/Swiss-Prot: <a href="http://www.uniprot.org/uniprot/Q9QYY0">Q9QYY0</a>;Human Entrez Gene: <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2549">2549</a>;Mouse Entrez Gene: <a href="http://www.ncbi.nlm.nih.gov/gene/14388">14388</a>;Rat Entrez Gene: <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=1725">Rn.1725</a>
|Protein names|| |
GRB2-associated-binding protein 1 , GRB2-associated binder 1 , Growth factor receptor bound protein 2-associated protein 1
|Protein function|| |
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).
|Protein sequence and domain|| |
Belongs to the GAB family. / Contains 1 PH domain.
|Protein post-translational modifications|| |
Phosphorylated in response to FGFR1 activation. Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains. Phosphorylated on tyrosine residues by HCK upon IL6 signaling.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="http://antibodyplus.com/product-tag/Gab/">Gab</a><br><a href="http://antibodyplus.com/product-tag/Signaling-Intermediates/"> (View all antibody categories related to Signaling Intermediates)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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