Rabbit polyclonal GABARAPL1 antibody (A7790)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GABARAPL1 antibody (A7790)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GABARAPL1 antibody.

Alternative names:

Check alternative names for the antibody

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ATG8 antibody, GEC1 antibody, APG8L antibody, ATG8B antibody, ATG8L antibody, APG8-LIKE antibody
APG8 like antibody|APG8L antibody|ATG8 antibody|ATG8B antibody|ATG8L antibody|Early estrogen regulated protein antibody|Early estrogen-regulated protein antibody|GABA antibody|GABA(A) receptor associated protein like 1 antibody|GABA(A) receptor-associated protein-like 1 antibody|GABARAPL1 a antibody|GABARAPL1 antibody|Gamma aminobutyric acid receptor associated protein like 1 antibody|Gamma-aminobutyric acid receptor-associated protein-like 1 antibody|GBRL1_HUMAN antibody|GEC 1 antibody|GEC-1 antibody|GEC1 antibody|Glandular epithelial cell protein 1 antibody|Anti-GABARAPL1 antibody (ab86497)

SCBT cat No:

Name

Rabbit polyclonal GABARAPL1 antibody

Catalogue No.

A7790

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GABARAPL1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 14kDa/Observed: Refer to figures

Formulation

GABARAPL1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GABARAPL1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ATG8 antibody, GEC1 antibody, APG8L antibody, ATG8B antibody, ATG8L antibody, APG8-LIKE antibody

Database links

Human UniProt/Swiss-Prot:Q9H0R8

Protein names

ATG8, GEC1, APG8L, ATG8B, ATG8L, APG8-LIKE

Protein function

Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Protein tissue specificity

Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motoneurons in the embryo and in neurons involved in somatomotor and neuroendocrine functions in the adult, particularly in the substantia nigra pars compacta.

Protein sequence and domain

Belongs to the ATG8 family.

Protein post-translational modifications

The precursor molecule is cleaved by ATG4B to form the cytosolic form, GABARAPL1-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, GABARAPL1-II (By similarity). ATG4B also mediates the delipidation required for GABARAPL1 recycling when autophagosomes fuse with lysosomes .; The Legionella effector RavZ is a deconjugating enzyme that produces an ATG8 product that would be resistant to reconjugation by the host machinery due to the cleavage of the reactive C-terminal glycine.

Protein cellular localization

Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Lipid-anchor. Endoplasmic reticulum . Golgi apparatus . Cytoplasmic vesicle, autophagosome.

Note

AntibodyPlus can customize GABARAPL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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