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Rabbit polyclonal GABARAPL1 antibody (A7790)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal GABARAPL1 antibody (A7790)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandATG8 antibody, GEC1 antibody, APG8L antibody, ATG8B antibody, ATG8L antibody, APG8-LIKE antibody
APG8 like antibody|APG8L antibody|ATG8 antibody|ATG8B antibody|ATG8L antibody|Early estrogen regulated protein antibody|Early estrogen-regulated protein antibody|GABA antibody|GABA(A) receptor associated protein like 1 antibody|GABA(A) receptor-associated protein-like 1 antibody|GABARAPL1 a antibody|GABARAPL1 antibody|Gamma aminobutyric acid receptor associated protein like 1 antibody|Gamma-aminobutyric acid receptor-associated protein-like 1 antibody|GBRL1_HUMAN antibody|GEC 1 antibody|GEC-1 antibody|GEC1 antibody|Glandular epithelial cell protein 1 antibody|Anti-GABARAPL1 antibody (ab86497)
SCBT cat No:
| Name | Rabbit polyclonal GABARAPL1 antibody |
|---|---|
| Catalogue No. | A7790 |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human GABARAPL1 |
| Host | Rabbit |
| Applications | WB, IHC |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 14kDa/Observed: Refer to figures |
| Formulation | GABARAPL1 antibody was tube-contained. |
| Purification | GABARAPL1 antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Alternative antibody names | ATG8 antibody, GEC1 antibody, APG8L antibody, ATG8B antibody, ATG8L antibody, APG8-LIKE antibody |
| Database links | Human UniProt/Swiss-Prot:Q9H0R8 |
| Protein names | ATG8, GEC1, APG8L, ATG8B, ATG8L, APG8-LIKE |
| Protein function | Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. |
| Protein tissue specificity | Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motoneurons in the embryo and in neurons involved in somatomotor and neuroendocrine functions in the adult, particularly in the substantia nigra pars compacta. |
| Protein sequence and domain | Belongs to the ATG8 family. |
| Protein post-translational modifications | The precursor molecule is cleaved by ATG4B to form the cytosolic form, GABARAPL1-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, GABARAPL1-II (By similarity). ATG4B also mediates the delipidation required for GABARAPL1 recycling when autophagosomes fuse with lysosomes .; The Legionella effector RavZ is a deconjugating enzyme that produces an ATG8 product that would be resistant to reconjugation by the host machinery due to the cleavage of the reactive C-terminal glycine. |
| Protein cellular localization | Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Lipid-anchor. Endoplasmic reticulum . Golgi apparatus . Cytoplasmic vesicle, autophagosome. |
| Note | AntibodyPlus can customize GABARAPL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
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