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Rabbit polyclonal GABRB2 antibody (A1876)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal GABRB2 antibody.
Check alternative names for the antibodyExpand
GABA antibody|GABA(A) receptor beta 2 antibody|GABA(A) receptor subunit beta-2 antibody|GABA-A receptor, beta-2 polypeptide antibody|GABRB2 antibody|Gamma aminobutyric acid (GABA) A receptor, beta 2 antibody|Gamma aminobutyric acid A receptor beta 2 antibody|Gamma-aminobutyric acid receptor subunit beta-2 antibody|Gamma-aminobutyric-acid receptor subunit beta-2 antibody|GBRB2_HUMAN antibody|Anti-GABA A Receptor beta 2 antibody (ab186875)
SCBT cat No: sc-7362|sc-31429|sc-133601|sc-7363|sc-31427|sc-31428|
Rabbit polyclonal GABRB2 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human GABRB2
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 59kDa/Observed: Refer to Figures
GABRB2 antibody was tube-contained.
GABRB2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
|Protein tissue specificity|| |
Isoform 1 and isoform 2 show reduced expression in schizophrenic brain. Isoform 3 shows increased expression in schizophrenic and bipolar disorder brains while isoform 4 shows reduced expression.
|Protein sequence and domain|| |
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB2 sub-subfamily.
|Protein cellular localization|| |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.
AntibodyPlus can customize GABRB2 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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