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Rabbit polyclonal GAD2 antibody (A0971)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal GAD2 antibody (A0971)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandGAD2 antibody,GAD65 antibody,MGC161605 antibody,MGC161607 antibody
65 kDa glutamic acid decarboxylase antibody|67 kDa glutamic acid decarboxylase antibody|GAD 65 antibody|GAD 67 antibody|GAD1 antibody|GAD2 antibody|Glutamate decarboxylase 1 antibody|Glutamate decarboxylase 2 antibody|Glutamate decarboxylase 2 pancreatic islets and brain 65kDa antibody|Glutamate decarboxylase 65 kDa isoform antibody|Glutamate decarboxylase 67 kDa isoform antibody|SCP antibody|Anti-GAD65 + GAD67 antibody (ab11070)
SCBT cat No: sc-7513|sc-365180|sc-390383|sc-28376|sc-5602|sc-58531|sc-7512|
| Name | Rabbit polyclonal GAD2 antibody |
|---|---|
| Catalogue No. | A0971 |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human GAD2 |
| Host | Rabbit |
| Applications | WB, IHC, IF |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 65kDa/Observed: Refer to Figures |
| Formulation | GAD2 antibody was tube-contained. |
| Purification | GAD2 antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Alternative antibody names | GAD2 antibody,GAD65 antibody,MGC161605 antibody,MGC161607 antibody |
| Database links | Human UniProt/Swiss-Prot:Q05329 |
| Protein names | GAD2,GAD65,MGC161605,MGC161607 |
| Protein function | Catalyzes the production of GABA. |
| Protein sequence and domain | Belongs to the group II decarboxylase family. |
| Protein post-translational modifications | Phosphorylated; which does not affect kinetic parameters or subcellular location.; Palmitoylated; which is required for presynaptic clustering. |
| Protein cellular localization | Cytoplasm, cytosol . Cytoplasmic vesicle . Cell junction, synapse, presynaptic cell membrane ; Lipid-anchor . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Note: Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters. |
| Background | The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid (1). GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems (2) and are thought to be involved in synaptic transmission (3) and insulin secretion (4), respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes (5). Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2 (6). |
| Research area | All research areas>Neurobiology>GAD |
| Note | AntibodyPlus can customize GAD2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
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