Rabbit polyclonal GAD2 antibody (A0971)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal GAD2 antibody (A0971)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GAD2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

GAD2 antibody,GAD65 antibody,MGC161605 antibody,MGC161607 antibody
65 kDa glutamic acid decarboxylase antibody|67 kDa glutamic acid decarboxylase antibody|GAD 65 antibody|GAD 67 antibody|GAD1 antibody|GAD2 antibody|Glutamate decarboxylase 1 antibody|Glutamate decarboxylase 2 antibody|Glutamate decarboxylase 2 pancreatic islets and brain 65kDa antibody|Glutamate decarboxylase 65 kDa isoform antibody|Glutamate decarboxylase 67 kDa isoform antibody|SCP antibody|Anti-GAD65 + GAD67 antibody (ab11070)

SCBT cat No: sc-7513|sc-365180|sc-390383|sc-28376|sc-5602|sc-58531|sc-7512|

Name

Rabbit polyclonal GAD2 antibody

Catalogue No.

A0971

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GAD2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 65kDa/Observed: Refer to Figures

Formulation

GAD2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GAD2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GAD2 antibody,GAD65 antibody,MGC161605 antibody,MGC161607 antibody

Database links

Human UniProt/Swiss-Prot:Q05329

Protein names

GAD2,GAD65,MGC161605,MGC161607

Protein function

Catalyzes the production of GABA.

Protein sequence and domain

Belongs to the group II decarboxylase family.

Protein post-translational modifications

Phosphorylated; which does not affect kinetic parameters or subcellular location.; Palmitoylated; which is required for presynaptic clustering.

Protein cellular localization

Cytoplasm, cytosol . Cytoplasmic vesicle . Cell junction, synapse, presynaptic cell membrane ; Lipid-anchor . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Note: Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.

Background

The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid (1). GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems (2) and are thought to be involved in synaptic transmission (3) and insulin secretion (4), respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes (5). Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2 (6).

Research area

All research areas>Neurobiology>GAD
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize GAD2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!