Rabbit polyclonal GADD45A antibody (A1797)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GADD45A antibody (A1797)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GADD45A antibody.

Alternative names:

Check alternative names for the antibody

Expand

DDIT1 antibody, GADD45 antibody
DDIT 1 antibody|DDIT-1 antibody|DDIT1 antibody|DNA damage inducible transcript 1 antibody|DNA damage-inducible transcript 1 protein antibody|GA45A_HUMAN antibody|GADD45 antibody|GADD45A antibody|Growth arrest and DNA damage inducible 45 alpha antibody|Growth arrest and DNA damage inducible alpha antibody|Growth arrest and DNA damage-inducible protein GADD45 alpha antibody|Anti-GADD45A antibody – Aminoterminal end (ab76664)

SCBT cat No: sc-796|sc-792|sc-6850|sc-48394|sc-797|

Name

Rabbit polyclonal GADD45A antibody

Catalogue No.

A1797

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GADD45A

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 18kDa/Observed: Refer to Figures

Formulation

GADD45A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GADD45A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DDIT1 antibody, GADD45 antibody

Database links

Human UniProt/Swiss-Prot:P24522

Protein names

DDIT1, GADD45

Protein function

In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

Protein sequence and domain

Belongs to the GADD45 family.

Protein cellular localization

Nucleus .

Background

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research area

All research areas>Tumor Suppressor/Apoptosis>GADD
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize GADD45A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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